Cerebral palsy is caused by injuries or abnormalities of the brain. Most of these problems occur as the baby grows in the womb. But they can happen at any time during the first 2 years of life, while the baby's brain is still developing.
In some people with cerebral palsy, parts of the brain are injured due to a low level of oxygen (hypoxia) in the area. It is not known why this occurs.
Premature infants have a slightly higher risk of developing cerebral palsy. Cerebral palsy may also occur during early infancy as a result of several conditions, including:
In some cases, the cause of cerebral palsy is never determined.
Symptoms of cerebral palsy can be very different between people with this group of disorders. Symptoms may:
Be very mild or very severe
Only involve one side of the body or both sides
Be more pronounced in either the arms or legs, or involve both the arms and legs
Symptoms are usually seen before a child is 2 years old. Sometimes symptoms begin as early as 3 months. Parents may notice that their child is delayed in reaching developmental stages such as sitting, rolling, crawling, or walking.
There are several different types of cerebral palsy. Some people have a mixture of symptoms.
Symptoms of spastic cerebral palsy, the most common type, include:
Muscles that are very tight and do not stretch. They may tighten up even more over time.
Abnormal walk (gait): arms tucked in toward the sides, knees crossed or touching, legs make "scissors" movements, walk on the toes
Joints are tight and do not open up all the way (called joint contracture)
Muscle weakness or loss of movement in a group of muscles (paralysis)
The symptoms may affect one arm or leg, one side of the body, both legs, or both arms and legs
The following symptoms may occur in other types of cerebral palsy:
Abnormal movements (twisting, jerking, or writhing) of the hands, feet, arms, or legs while awake, which gets worse during periods of stress
Call your health care provider if symptoms of cerebral palsy develop, especially if you know that an injury occurred during birth or early infancy.
Getting the proper prenatal care may reduce the risk of some rare causes of cerebral palsy. In most cases though, the injury causing the disorder is not preventable.
Pregnant mothers with certain medical conditions may need to be followed in a high-risk prenatal clinic.
Johnston MV. Encephalopathies. In: Kliegman RM, Stanton BF, St. Geme JW III, et al., eds. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa: Elsevier Saunders; 2011:chap 591.
Murphy KP. The adult with cerebral palsy. Orthop Clin N Am. 2010;41:595–605.
Nass R, Ross G. Developmental disabilities. In: Daroff RB, Fenichel GM, Jankovic J, Mazziotta JC, eds. Bradley’s Neurology in Clinical Practice. 6th ed. Philadelphia, Pa: Elsevier Saunders; 2012:chap 61.
Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology. 2010;74:336-343.
Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.